The main target of the LIFE-COMBASE Project is to promote the sustainable use of biocidal active substances from a life cycle perspective. To this end, an on-line information system based on the combination of evidence based decision support systems (EBDSS) and proven computational toxicology modelling approaches will be implemented.

The specific objectives of the project are the following:

  • Contribute to the fulfilment of the BPR (Biocides Product Regulation – 258/2012) and, in particular, to the 2009/128/EC Directive establishing a framework for Community action to achieve the sustainable use of pesticides (for its implementation in biocidal active substances).
  • Minimize the environmental effects associated to active substances, metabolites, degradation and reaction products from biocides. Aligned with present target, the human health impacts associated to biocides when indirectly exposed through the environment will be reduced.
  • Reduce the need of animal testing by promoting the use of computational tools for ecotoxicological effects prediction as a non-testing alternative to traditionally used assays.
  • Demonstrate the effectiveness of computational models to minimize the environmental impacts from active substances in biocidal products.
  • Demonstrate the suitability of developed models to alternative products (Plant Protection Products; and chemicals in general –REACH-).
  • Complementarities establishment with previously developed LIFE Projects, (ANTARES, CALEIDOS & PROSIL, amongst other). Along with previous projects in the present field, the COMBASE Projects seeks to contribute to the standardisation of the use of non-testing methods by the chemical industry.
  • Contribute to the consolidation of the knowledge base on the hazard of biocide active substances from a life cycle perspective
  • Disseminate the project results to a large community of SMEs and relevant stakeholders.